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KMID : 1197720100030020042
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대한파킨슨병 및 이상운동질환 학회지
2010 Volume.3 No. 2 p.42 ~ p.44
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Cardiac [123]I-metaiodobenzylguanidine Scintigraphy in a Patient with Familial Parkinsonism with Parkin Gene Mutation
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Kim Young-Do
Song In-Uk
Kim Joong-Seok
Chung Sung-Woo
Lee Kwang-Soo
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Abstract
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A decreased cardiac 123I-metaiodobenzylguanidine (123I-MIBG) uptake has been used as a powerful tool to identify Lewy body disease, such as idiopathic parkinson’s disease (IPD). We performed cardiac 123I-MIBG scintigraphy in patient with autosomal recessive juvenile parkinsonism (ARJP) with parkin gene mutation (PARK2). The findings showed normal cardiac 123I-MIBG uptake. Therefore, although the clinical features of ARJP are sometimes quite similar to those of late-onset IPD, cardiac 123I-MIBG scintigraphy may be used as a valuable tool to identify patients with IPD and to distinguish them from patients with other parkinsonian syndromes.
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KEYWORD
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[123]I-metaiodobenzylguanidine, Autosomal recessive juvenile parkinsonism, Parkin gene
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